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Molecular Pathology

Overview

In Department of Molecular Pathology, we are studying pathogenesis and pathophysiology of the diseases, especially in digestive organs. In addition to the basic research, we also take part in clinical practice as clinical pathologists in Chiba University Hospital.

Associate Professor:
Takashi Kishimoto, M.D., Ph.D.

TEL:+81-43-226-2059
FAX:+81-43-226-2063
e-mail:tkishi●faculty.chiba-u.jp
URL: https://www.m.chiba-u.jp/dept/molecular-pathology/

※　Please change "●" mark to at-mark if you send emails.

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Research & Education

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  1. Experimental pathology
    Pathological study of gastrointestinal cancer
    --- Molecular pathology of AFP-producing adenocarcinoma and its highly malignant phenotype
    --- Poor prognostic factors in invasive pancreatic ductal carcinoma
    --- Study on invasive metastasis of colorectal cancer

  2. Histopathological analysis
    --- Pancreatobiliary diseases
    --- AFP-producing tumors and hepatoid adenocarcinoma

  3. Education
    --- Pathology lectures, practical training, and scholarship programs at the School of Medicine and Graduate School of Medicine

Recent Publications

  1. Kouch Y, Yamashita K, Harada S, et al. Solid serous neoplasm of the pancreas with locally aggressive behaviors. Pathol Int 2021;71:795-797.
  2. Oka Y, Takano S, Kouchi Y, et al. Simultaneous brain and lung metastases of pancreatic ductal adenocarcinoma after curative pancreatectomy: a case report and literature review. BMC Gastroenterol. 2021;21:9.
  3. Yamamura N, Fugo K, Kishimoto T. Forkhead box protein A2, a pioneer factor for hepatogenesis, is involved in the expression of hepatic phenotype of alpha-fetoprotein-producing adenocarcinoma. Pathol Res Pract. 2017;213:1082-1088.
  4. Kishimoto T, Fugo K, Kiyokawa T. Intracellular position of G2/M-phase nuclei in neoplastic and non-neoplastic pseudostratified glands suggests the occurrence of interkinetic nuclear migration. Med Mol Morphol. 2013;46:210-6
  5. Yamamura N, Kishimoto T.　Epigenetic regulation of GATA4 expression by histone modification in AFP-producing gastric adenocarcinoma. Exp Mol Pathol. 2012;93:35-39.