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Diagnostic Pathology

Overview

In our department, we aim to understand the pathology of various lesions in an integrated manner by grossly examining the affected organs, analyzing microscopic features and further clarifying genetic/molecular abnormalities in the background. As a result, we can contribute to medical treatment in clinical settings by providing useful information on diagnosis and treatment. We are advancing research and education mainly on neoplastic diseases and diagnostic surgical pathology/cytology in general as described below:

Professor:
Junichiro Ikeda, M.D., Ph.D.

TEL:+81-43-226-2508
FAX:+81-43-226-2180
e-mail:jikeda●chiba-u.jp
URL: https://www.m.chiba-u.jp/dept/humpathol/

※　Please change "●" mark to at-mark if you send emails.

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Research & Education

  1. Pathology of neoplastic diseases
    ・ Pulmonary tumor: clinicopathological, immunohistochemical and genetic analysis
    ・ Gastrointestinal tumor: clinicopathological, immunohistochemical and genetic analysis
    ・ Malignant lymphoma: clinicopathological, immunohistochemical and genetic analysis ・ Cancer-initiating cells

  2. Diagnostic surgical pathology

  3. Diagnostic cytopathology
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Involvement of squamous cell carcinoma in situ and small cell carcinoma in situ(Ota M et al. Histopathology, 2021)

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Effect of plasma-treated methionine solution on ALDH activity in cancer cells(Uchida G, Ikeda JI et al. Sci Rep, 2019)

Recent Publications

  1. Ota M, Nakatani Y, Nakajima T, Hiroshima K, Motoi N, Yoshino I, Ikeda JI.　Pulmonary microinvasive small cell carcinoma with extensive in situ component identified after photodynamic therapy for ‘squamous cell carcinoma in situ’: A case report. Histopathology. 2021 May;78(6):912-916.
  2. Okabe A, Huang KK, Matsusaka K, Fukuyo M, Xing M, Ong X, Hoshii T, Usui G, Seki M, Mano Y, Rahmutulla B, Kanda T, Suzuki T, Rha SY, Ushiku 　T, Fukayama M, Tan P, Kaneda A. Cross-species chromatin interactions drive transcriptional rewiring in Epstein-Barr virus-positive gastric adenocarcinoma. Nat Genet. 2020 Sep;52(9):919-930.
  3. Uchida G, Mino Y, Suzuki T, Ikeda JI, Suzuki T, Takenaka K, Setsuhara Y. Decomposition and oxidation of methionine and tryptophan following irradiation with a nonequilibrium plasma jet and applications for killing cancer cells. Sci Rep. 2019 Apr 29;9(1):6625.