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Anesthesiology

Overview

It is our mission to achieve safety and comfort of every single patient undergoing surgery, receiving palliative care or suffering chronic pain and dyspnea. In accord with our mission, we conduct both clinical and basic research testing novel approaches to solve the clinical problems and clinically-meaningful hypotheses based on our own clinical experiences.

Professor:
Shiroh Isono, M.D., Ph D.

TEL:+81-43-226-2155
FAX:+81-43-226-2156
e-mail:shirohisono●yahoo.co.jp
URL: https://www.ho.chiba-u.ac.jp/dept/masui/

※　Please change "●" mark to at-mark if you send emails.

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Research & Education

  1. Clinical studies for achieving safe and comfortable perioperative management for patients
    　Perioperative upper airway function and managements of obstructive sleep apnea patients
    　Development of new respiratory monitoring systems
    　Perioperative hemodynamic managements and 　cardiovascular complications
    　Postoperative pain managements
  2. Education and clinical studies in palliative care medicine
    　Mechanisms and managements of various unpleasant symptoms such as pain and dyspnea
  3. Basic research on respiratory control
    　Mechanisms of gasping, sigh and their pathophysiological roles

Recent Publications

  1. Sakaguchi Y, et al. Combination therapy of high-flow nasal cannula and upper-body elevation for postoperative sleep-disordered breathing: Randomized crossover trial. Anesthesiology. 2022 Jul 1;137(1):15-27.
  2. Ide A, et al. Rocuronium versus saline for effective facemask ventilation during anesthesia induction: a double-blinded randomized placebo-controlled trial. BMC Anesthesiol. 2022 Jun 3;22(1):173.
  3. Taiji S, et al. Changes in breathing pattern during severe hypothermia and autoresuscitation from hypothermic respiratory arrest in anesthetized mice. Physiol Rep. 2021 Dec;9(23):e15139.
  4. Shinohara A, et al. Hypercapnia versus normocapnia for emergence from desflurane anaesthesia: Single-blinded randomised controlled study. Eur J Anaesthesiol. 2021 Nov 1;38(11):1148-1157.
  5. Tarao K, et al. Risk factors including preoperative echocardiographic parameters for post-induction hypotension in general anesthesia. J Cardiol. 2021 Sep;78(3):230-236.
  6. Suganuma E, et al. Recovery of lower oesophageal barrier function: a pilot study comparing a mixture of atropine and neostigmine and sugammadex: A randomised controlled pilot study. Eur J Anaesthesiol. 2021 Aug 1;38(8):856-864.
  7. Hasegawa M, et al. Effects of opioids on respiration assessed by a contact-free unconstraint respiratory monitor with load cells under the bed in patients with advanced cancer. J Appl Physiol (1985). 2021 Jun 1;130(6):1743-1753.